I think Denusomab increases risk of infection not alendronate

Denusomab is RANKL inhibitor and Osteoclast deactivator. Both Denusomab and alendronate cause osteoclastic deactivation. But only Denusomab cause increased risk of infection in the form of Cellulitis . Reason being RANKL Inhibition by Denusomab not only causes RANKL Inhibition of Osteoclast but it calso causes inhibition of RANKL on T cells and Dendritic cells of immune system ----- Decreased Immune system --- Increased Risk of Infection especially in CKD Elderly and DM Patients

Iam adoctor

Conditions with haemachromatosis

Pt with af and old pe on warfarin present with gouty attack

What the first line treatment

Questions specific for DM

About IgA

Is Frist sign oh hypokalemia

Seen in tricuspid regurgitation where loss of x descend and fusion of c & v wave produces larger v wave

To assess the knee joint effusion

Acts on serotonin

Hi Everyone,

I hope you're doing well. I know you're likely in the midst of preparing for your MRCP Part 1 exam, so I'll keep this brief but informative. Here are my experiences and recommendations for the MRCP Part 1 exam.

Booking the Exam: First and foremost, book your exam as soon as possible. The psychological commitment of having a set date can significantly boost your motivation and focus. Once you have a deadline, your study efforts will become more structured and productive.

Study Resources: For my preparation, I primarily used PassMedicine. The community feature, where you can discuss questions and answers with other exam takers, was extremely helpful. I also did a few mock papers from Pastest. While neither resource perfectly mirrored the actual exam questions, I believe either one would be sufficient on its own. Additionally, I found the Qbank at MedAll to be excellent.

Study Routine: Since I was working during my preparation period, I couldn't commit a lot of time each day. I aimed to do about 50 questions per session, which was typically all I could manage in a day. Discussing the questions with a study partner over Discord was particularly beneficial. I'm considering creating a MedAll Discord community, which might be helpful for all of you. Let me know if you're interested.

Official MRCP Mock Exam: Make sure to complete the official MRCP mock exam available on their website. It provides a realistic feel of the actual exam and, for me, accurately reflected my final score.

Exam Day: I took the exam from home. Ensure your network connection is reliable and complete the IT checks provided well in advance. A proctor will monitor the exam, and they're quite helpful. You get one break during the exam, so plan it wisely, especially if you're drinking coffee, as it acts as a diuretic.

Time Management: The exam time was sufficient; I finished both papers with an hour to spare. You can use this extra time to review your answers or end the exam early if you're confident.

Results: Expect to receive your results via email or on the MyMRCP portal about a month after the exam.

Thank you for reading. I hope you found this helpful. If you need any further assistance, feel free to leave a comment, and I'll be happy to help.

Best of luck with your studies and the exam!

One

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