Refetoff Syndrome - Wrong Vignette
Posted by Camila Dias, a day ago, 0 comments
Refetoff Syndrome - Wrong Vignette
Referoff: Resistance to Thyroid Hormone (RTH), is a rare genetic disorder where the body's tissues respond poorly to thyroid hormones. This causes the thyroid to overproduce hormones, resulting in a unique lab pattern: elevated thyroid hormones (Free T3 and Free T4) with an unsuppressed or slightly high TSH (thyroid-stimulating hormone).
Posted by Camila Dias, a day ago, 0 comments
Exam prep
Posted by Munisa Kuranbekova, 28 Apr 2026, 1 comments
Exam prep
Here, I want to review my mistakes and learn something new
Posted by Munisa Kuranbekova, 28 Apr 2026, 1 comments
Cystic fibrosis
Posted by Ahmed Abdullahi, 16 Mar 2026, 0 comments
Cystic fibrosis
Chest radiology reveals bronchiectasis
Posted by Ahmed Abdullahi, 16 Mar 2026, 0 comments
scurvy
Posted by Gabriel Trujillo, 17 Dec 2025, 0 comments
scurvy
OSTEOGENESIS IMPERFECTA does not produce scurvy, which is caused by a vitamin C deficiency
Posted by Gabriel Trujillo, 17 Dec 2025, 0 comments
Answer is wrong
Posted by Thomas Lawton, 7 Dec 2025, 0 comments
Answer is wrong
Karyotyping the mother is NOT the correct tool for estimating the risk of Down syndrome in her fetus.
The mother is phenotypically normal, so she cannot have full trisomy 21 herself.
The only scenario where the mother's karyotype matters is if she carries a balanced Robertsonian translocation involving chromosome 21 — but this is rare, and the question gives no suggestion of such.
The given answer confuses:
- maternal meiotic nondisjunction risk (age-related, statistical)
- vs.
- heritable translocation Down syndrome (very rare)
Posted by Thomas Lawton, 7 Dec 2025, 0 comments
ADDISON DISEASE
Posted by Gabriel Trujillo, 4 Dec 2025, 0 comments
ADDISON DISEASE
reduced cortisol, sodio, aldosterona but incresed K+
Posted by Gabriel Trujillo, 4 Dec 2025, 0 comments
New member
Posted by Fortune Rufus, 27 Jan 2025, 1 comments
New member
Hi everyone
My name is Fortune
I'm an IMG from Nigeria and 2 years away from graduation
I'm looking to specialise in paediatrics neonatology
Posted by Fortune Rufus, 27 Jan 2025, 1 comments
eryhropoitin and hypertension
Posted by Mohammad Ameen, 17 Jun 2025, 0 comments
eryhropoitin and hypertension
mech by which EP induces HTN
- inhibits Ach induced vasodialation vaso dialation
- platelet aggregates
- increased levels of Endothelin -1
renal cell carcinoma - increased EP
Posted by Mohammad Ameen, 17 Jun 2025, 0 comments
Review
Posted by mauricio calderon, 25 Aug 2025, 0 comments
Review
She is having problems in The pasta month. And not over 6 months period
Posted by mauricio calderon, 25 Aug 2025, 0 comments
why is option 5 not more suitable
Posted by Anusree Chalamalasetty, 23 Mar 2024, 0 comments
why is option 5 not more suitable
she did not have to acquire new skills after her injury and lack of adaptation would cause weakness in left leg
Posted by Anusree Chalamalasetty, 23 Mar 2024, 0 comments
Welcome & introductions
Posted by Team MedAll, 25 Jan 2024, 3 comments
Welcome & introductions
Welcome to the USMLE Step 1 Community. Why not take some time to introduce yourself, let us know what you do, where you come from and what your healthcare interests are.
Posted by Team MedAll, 25 Jan 2024, 3 comments
Streptococcus can be in clusters?
Posted by Lucia Tello, 7 May 2024, 2 comments
Streptococcus can be in clusters?
In the question says "Blood cultures grew gram-positive cocci in clusters" which made me think of Staph but the medical history madde me think of Strep. Now, I don´t know if it was a coinfection or what happened there
Posted by Lucia Tello, 7 May 2024, 2 comments
three possible correct answers?
Posted by Ali Elian, 28 Dec 2024, 1 comments
three possible correct answers?
Struvite stones, form only when the upper urinary tract is infected with urease-producing bacteria such as Proteus mirabilis, Klebsiella pneumoniae, Staphylococcus,
saprophyticus.
Posted by Ali Elian, 28 Dec 2024, 1 comments
Review of Question Vignette or Answer Choices
Posted by Alexa Szatkowski, 16 Sep 2025, 0 comments
Review of Question Vignette or Answer Choices
While ETEC is known to be the primary cause of Traveler's diarrhea based on its watery characteristic, its heat-labile/stable enterotoxins do not cause inflammation or invasion. On the other hand, EIEC's microbes invade the intestinal mucosa, causing necrosis and inflammation similar to that of Shigella, which leads to watery diarrhea progressing to blood and mucus in the stool. Therefore, I think this question needs to be reviewed to reform the stem to point towards ETEC or change the answer choices.
Posted by Alexa Szatkowski, 16 Sep 2025, 0 comments
Why is the answer not prolactin levels?
Posted by Anusree Chalamalasetty, 21 Mar 2024, 1 comments
Why is the answer not prolactin levels?
they mentioned normal limits of RBC and glucose. testosterone induces erythropoiesis and decrease in it would decrease the RBCs too
Posted by Anusree Chalamalasetty, 21 Mar 2024, 1 comments