It says the urine has increased osmolality and plasma decreased osmolality, but in DI, when there is no ADH it should be the opposite, urine diluted and plasma concentrated. Please give feedback

No murmur or abnormalities that suggest vavulopathy.

The spina bifida occurs in a Higher rate in this population...

Might be usefull to measure new cases because talks about speed

if secretion is increased, phosphate levels then should be decreased, not increased like the vignette said, it is wrong

Why is it pneumoconiosis if the patient has no history of smoking and works in a textile factory?

Just need to go through with this disease

Hi everyone

My name is Fortune

I'm an IMG from Nigeria and 2 years away from graduation

I'm looking to specialise in paediatrics neonatology

I’m thrilled to share that I passed the USMLE Step 1 exam last night, and I couldn’t be happier! 🎉

I’ve been a silent observer in this community, absorbing all the advice and motivation, but now it feels like the perfect moment to give back. The tips, study strategies, and shared experiences here were incredibly valuable during my journey.

Here’s how I did it: I started studying intensively about six weeks ago, dedicating every available moment to preparing. My primary resources were First Aid, UWorld, and some well-chosen practice exams. Yesterday, on a bit of a whim, I decided to book the exam last-minute—and thankfully, it all worked out!

For anyone preparing, I can’t emphasize enough the importance of practice tests. They not only helped me identify my weak areas but also got me comfortable with the question style and pacing of the actual exam. Practice exams truly made a massive difference in my confidence and readiness.

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Good luck to everyone on their USMLE journey—you’ve got this! 💪

Struvite stones, form only when the upper urinary tract is infected with urease-producing bacteria such as Proteus mirabilis, Klebsiella pneumoniae, Staphylococcus,

saprophyticus.

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You certainly can calcúlate the positive predictive value, you have 85% of the deseased that tested positive, so they are true positives, you also have 15% that tested positive but have no symptoms so they are false positive, since PPV= TP/TP+FP x 100, then you have all the information you need in order to obra in the positive predictive value, so i think tour answer might be wrong..

A 58-year-old man presents with history of recurrent rashes that became severe in the last week. The rashes were erythematous with a fine, sandpaper-like texture. He also reports having a fever and symptoms of a sore throat two weeks prior to the rash. Examination reveals a 'strawberry tongue'. Based on the history and physical examination, what mechanism is the most likely cause of this patient's symptoms?

correct answer: type 4 hypersensitivity

I picked the answer "direct toxins from bacterial exotoxins"

why is this type 4 hypersensitivity? please explain

The patient in this case is 70 years old. At this age, an corneal arcus is fairly common. Given the circumstances, FH would not be my first thought. If the patient was young (<50), hyperlipidemia/FH would be a more likely differential diagnosis.

Hey guys! I'm starting a group exclusively for doubt clearance and discussion of UWorld questions ( or any other question bank). We can help each other out by explaining topics to our peers in a mutually beneficial way. Please join using this link: https://chat.whatsapp.com/HQcMoouB4jHDcAjdTl8m2E

they mentioned normal limits of RBC and glucose. testosterone induces erythropoiesis and decrease in it would decrease the RBCs too

Welcome to the USMLE Step 1 Community. Why not take some time to introduce yourself, let us know what you do, where you come from and what your healthcare interests are.

Herpes Simplex Virus

the explanation should include how colon plays an important role in contributing to the hyperkalemia. constipation meaning the "poop feels stuck" so additional absorption wouldn't take place

Are you looking for a study partner? This is a great place to offer help or look for support.

did not hear about this disease before, must review