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American Board of Internal Medicine Community
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7 Jan 2025
Rabies
Question:
A 45-year-old man who recently returned from a camping trip with his dog in Arizona presents with fever, headache, and a behavior change characterized by agitation. The patient's behavior worsens over the subsequent several days with fluctuating levels of consciousness and paralysis. A lumbar puncture is performed, which reveals an abnormality in cerebrospinal fluid. Histologic examination of an autopsy brain specimen shows a neuron with a cytoplasmic inclusion body as depicted in the picture. Which of the following organisms is most likely to cause the patient's underlying condition?
Options:
A)Borrelia burgdorferi
B)Toxoplasma gondii
C)Rabies virus
D)Naegleria fowleri
E)Treponema pallidum
Rabies
Question:
A 45-year-old man who recently returned from a camping trip with his dog in Arizona presents with fever, headache, and a behavior change characterized by agitation. The patient's behavior worsens over the subsequent several days with fluctuating levels of consciousness and paralysis. A lumbar puncture is performed, which reveals an abnormality in cerebrospinal fluid. Histologic examination of an autopsy brain specimen shows a neuron with a cytoplasmic inclusion body as depicted in the picture. Which of the following organisms is most likely to cause the patient's underlying condition?
Options:
A)Borrelia burgdorferi
B)Toxoplasma gondii
C)Rabies virus
D)Naegleria fowleri
E)Treponema pallidum