The boy's symptoms are indicative of osteogenesis imperfecta, a condition characterized by defects in collagen synthesis. Vitamin C is essential for hydroxylation of proline and lysine residues in collagen synthesis. Without these reactions, collagen fibers are less stable, which can contribute to the symptoms of this disorder.

Vitamin D deficiency usually leads to rickets in children or osteomalacia in adults, conditions characterized by softening and deformation of bones.

Vitamin E is an important antioxidant and its deficiency can lead to neurological complications.

Vitamin K is necessary for the synthesis of proteins involved in blood clotting. Deficiency can cause bleeding disorders, but not bone fragility.