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The ARIA Escalation Call
Question 1 of 25
A 70-year-old woman presents with recent episodes of confusion and disorientation reported by her family. She is withdrawn and has been treated for major depressive disorder for the past year. You suspect she may have early symptoms and signs of Alzheimer’s disease (AD). Which of the following pathological processes occurs earliest in AD and may be detected using neuroimaging modalities?
A
A. Tau-mediated neuronal injury
B
B. Brain structure changes
C
C. Amyloid-beta accumulation
D
D. Altered cognition
E
E. Neuroinflammation
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