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‘a little refresher’ Lecture 6: Introduction to MIMS 30/09/22 EdMedSocBrief overview • What is MIMS? • How the material is delivered • List of key concepts • How do the exams work? • What I wish I knew • A note about practicals • Questions?What is MIMS? • MIMS = Molecules in Medical Science • i.e. a fancy name for Biochemistry! • Lots of biochemical cycles and understanding how cells work at a molecular levelHow is the material delivered? • Lectures: usually 2 – 3/week • Supervisions: organised by college • Practicals: usually 1/term • Problem-based learning exercise (PBL): 1 in Michaelmas (term 1), 1 in Lent (term 2)List of key concepts • NB: this is from when we were in first year, so there may have been some changes since – Moodle will tell you everything you need! Michaelmas • Diabetes mellitus • Protein structure and function • Bioenergetics and metabolism • Membrane dynamics and function • Hormone signalling in cells • Protein recognition and a bit on antibodiesList of key concepts cont. Lent (genome and cancer term) • DNA and RNA • Replication, DNA repair, transcription, translation • Disease genetics • Single mutation (monogenic) diseases, penetrance • Complex diseases, GWAS • Cancer and the cell cycle • Cell deathList of key concepts cont. Easter (no new content) • A few lectures on imaging • Some lecturers organise revision lectures • ExamsHow do the exams work? • 3 exams in total (Section I, II and III) 1. Section I = MCQ (multiple choice question) paper, based on lecture material, 1 hour 2. Section II = Practical paper, based on MIMS practicals, 2 hours 3. Section III = Essay paper, based on whole course, 2 hours • NB: sections I and II are taken as a single 3 hour paper • Only sections I and II count towards 2nd MB • All sections count towards TriposWhat I wish I knew • It’s a marathon not a sprint!! • Try not to miss lectures where you can • Summarise key concepts as you go along • Maybe make a small list of key learning points from each lecture • Practise practise practise! (MCQs, essays, practical papers)A little bit on practicals • 1 per term, as mentioned before • 1) Proteins as the diagnostic markers for disease • 2) Mitochondria and metabolism • 3) Bioinformatics • Would recommend doing a bit of pre-reading before each practical, just to work out what the 2 hours will involveThank you for listening! • Any questions? • Please fill in the feedback form here: • https://tinyurl.com/32atvme4