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22 Nov 2025
Immunoglobulin
Question:
A 23-year-old woman comes to her physician with complaints of frequent episodes of spontaneous bleeding from her gums and recurrent ulcers in her mouth. She has had frequent episodes of sinusitis since childhood. On physical examination, she has multiple purulent ulcers all over her oral mucosa suggestive of oral thrush and pallor.Lab investigations reveal severe iron deficiency anemia. Her IgM levels are increased but IgA, IgG and IgE levels are decreased. Which of the following best explains patient's clinical presentation?
Options:
A)Selective IgA deficiency
B)Common variable immunodeficiency
C)X-linked agammaglobulinemia
D)Hyper IgM syndrome
E)DiGeorge Syndrome
Immunoglobulin
Question:
A 23-year-old woman comes to her physician with complaints of frequent episodes of spontaneous bleeding from her gums and recurrent ulcers in her mouth. She has had frequent episodes of sinusitis since childhood. On physical examination, she has multiple purulent ulcers all over her oral mucosa suggestive of oral thrush and pallor.Lab investigations reveal severe iron deficiency anemia. Her IgM levels are increased but IgA, IgG and IgE levels are decreased. Which of the following best explains patient's clinical presentation?
Options:
A)Selective IgA deficiency
B)Common variable immunodeficiency
C)X-linked agammaglobulinemia
D)Hyper IgM syndrome
E)DiGeorge Syndrome