ATRA causes differentiation of blast cells into mature cells, leading to functional granulocytes.
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Question:
A 42-year-old patient presents with symptoms of fatigue, easy bruising, and recurrent infections. Further investigation reveals a diagnosis of promyelocytic leukaemia. The patient is started on treatment with all trans retinoic acid. What is the mechanism of action of this medication and how it contributes to the management of promyelocytic leukaemia?
Options:
A)Leads to differentiation of mature cells into blast cells
B)Acts as a colony stimulating factor
C)Leads to differentiation of blast cells into mature cells
D)Leads to the prevention of blast cell division
E)Leads to apoptosis of blast cells
Review the answer
Question:
A 42-year-old patient presents with symptoms of fatigue, easy bruising, and recurrent infections. Further investigation reveals a diagnosis of promyelocytic leukaemia. The patient is started on treatment with all trans retinoic acid. What is the mechanism of action of this medication and how it contributes to the management of promyelocytic leukaemia?
Options:
A)Leads to differentiation of mature cells into blast cells
B)Acts as a colony stimulating factor
C)Leads to differentiation of blast cells into mature cells
D)Leads to the prevention of blast cell division
E)Leads to apoptosis of blast cells