Can you answer the questions about this case? Watch Prof Gain's session, who chairs a discussion on this topic in our Advanced Prostate Cancer Course
Mr. Smith, a 65-year-old retired teacher in good overall health, presented for his annual checkup. His routine blood work revealed an increasing trend in his prostate-specific antigen (PSA) levels over the past two years. After experiencing increased urinary frequency and nocturia, he was referred to a urologist. An MRI revealed a lesion in the left posterior peripheral zone of the prostate with suspected extraprostatic extension. A subsequent MRI fusion biopsy confirmed high-risk prostate cancer (Grade Group 4). A PSMA-PET scan further revealed an avid lymph node and sclerotic bone metastasis, indicating early (oligo) metastatic disease.
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What role could clinical trials play in Mr. Smith's treatment plan, and how can he be informed about the potential benefits and risks of participation?
What role could clinical trials play in Mr. Smith's treatment plan, and how can he be informed about the potential benefits and risks of participation?
What are the potential side effects of the different treatment options, and how should these be discussed with Mr. Smith to ensure informed decision-making?
What are the potential side effects of the different treatment options, and how should these be discussed with Mr. Smith to ensure informed decision-making?
Given Mr. Smith's active lifestyle and desire to maintain quality of life, what treatment approach might best align with his care goals and preferences?
Given Mr. Smith's active lifestyle and desire to maintain quality of life, what treatment approach might best align with his care goals and preferences?
How might the presence of the avid lymph node and bone metastasis influence the decision-making process regarding treatment choice?
How might the presence of the avid lymph node and bone metastasis influence the decision-making process regarding treatment choice?
What are the potential treatment options for Mr. Smith considering his age, health status, and newly diagnosed oligo-metastatic prostate cancer? What are the pros and cons of each option (surgery, radiation, ADT, chemotherapy)?
What are the potential treatment options for Mr. Smith considering his age, health status, and newly diagnosed oligo-metastatic prostate cancer? What are the pros and cons of each option (surgery, radiation, ADT, chemotherapy)?