This program is supported by an independent education grant from Ipsen. This online education program has been designed for healthcare professionals in the US. The content is not intended for healthcare professionals in any other country.

Credits: AMA PRA Category 1 Credits™ (0.25.00 hours)

Type of activity: Enduring material (Clinical Snapshot)

Launch date: 25 July 2026

Expiration date: 25 January 2027

Estimated time to complete this activity: 15 minutes

Who Should Participate

This program is designed for U.S.-based healthcare professionals involved in the Epithelioid Sarcoma care, including:

• Oncologists
• Pathologists
• Surgical Oncologists
• Sarcoma Specialists
• Orthopedic Oncologists
• Medical Oncologists
• Radiation Oncologists
• Dermatopathologists (for rare cutaneous ES presentations)
• Other relevant HCPs involved in diagnosing and managing ES

Faculty

Seth M. Pollack, MD is an oncologist and physician-scientist specializing in sarcoma and cancer immunotherapy. As the Director of the Sarcoma Program at Northwestern University, he focuses on developing new treatments for soft tissue sarcomas. His research primarily addresses why some tumors do not respond to traditional immunotherapy and investigates methods to improve the effectiveness of T-cell therapies in these "immune-cold" cancers.

Dr. Pollack leads several clinical trials, including first-in-human studies that test cytokine-based strategies and engineered T cells. He currently serves as the national chair for a Phase III trial evaluating immunotherapy combinations for advanced sarcoma. In addition to his clinical work, he contributes to the development of national treatment guidelines and serves on the advisory boards of several major sarcoma research foundations.

Hannah Abrams, MD is a hematology/oncology fellow at the Fred Hutch Cancer Center and a contributor to the medical education podcast The Curious Clinicians. Her clinical practice focuses on the management of hematologic malignancies, with a professional interest in the clinical reasoning and evidence-based foundations of modern oncology. Her recent health services research examines the socioeconomic and logistical barriers to advanced cellular therapies.

Continuing Education Information

Commercial support: This activity received monetary support through an independent education grant from Ipsen.

This continuing education activity will be provided by AffinityCE and MedAll. This activity will provide continuing education credit for physicians. A statement of participation is available to other attendees.

Disclosures

Dr Seth Pollack has disclosed financial interests or relationships within the past 24 months with the following ineligible companies: Advisory Board: Bayer, Rain Therapeutics, Deciphera, Ipsen, Daiichi-Sankyo, Replimune, SpringWorks, Adaptimmune, EMD Serono, Boehringer Ingelheim; Scientific Advisory Board: Attivare; Speaking/Speaker: Deciphera, SpringWorks; DSMB; Chair: SynOx.

Relationships with Bayer, Rain Therapeutics, Deciphera (Advisory Board), Ipsen, Daiichi-Sankyo, Replimune, SpringWorks (Advisory Board), Adaptimmune, EMD Serono, and Boehringer Ingelheim ended within the past 24 months. These disclosures are made in accordance with ACCME standards to ensure transparency and objectivity in continuing education. He does not intend to discuss non-FDA uses of drug products and/or devices.

Dr Hannah Abrams has no financial relationships within the past 24 months with the following ineligible companies to disclose. Dr Abrams intends to discuss non-FDA uses of drug products and/or devices only in relation to products for which s/he has no financial relationships and will disclose to the audience when these discussions take place.

AffinityCE staff, MedAll staff, as well as planners and reviewers, have no relevant financial relationships with ineligible companies to disclose.

Mitigation of Relevant Financial Relationships

AffinityCE adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible companies. All relevant financial relationships for anyone associated with the content of this activity were mitigated prior to the release of this program.

Activity Accreditation for Health Professions

Physicians

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and MedAll. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.

AffinityCE designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physician Assistants

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and MedAll. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.

AffinityCE designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physician assistants should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioners

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and MedAll. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.

AffinityCE designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.

Nurses & Other Professionals

All other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity.

System Requirements

Mobile device (e.g., large-format smart phone; laptop or tablet computer) or desktop computer with a video display of at least 1024 × 768 pixels at 24-bit color depth, capable of connecting to the Internet at broadband or faster speeds, with a current version Internet browser and popular document viewing software (e.g., Microsoft Office, PDF viewer, image viewer) installed. Support for streaming or downloadable audio-visual materials (e.g., streaming MP4, MP3 audio) in hardware and software may be required to view, review, or participate in portions of the program.

Unapproved and/or off-label use disclosure

AffinityCE/MedAll requires CE faculty to disclose to the participants:

1. When products or procedures being discussed are off-label, unlabeled, experimental, and/or investigational (not US Food and Drug Administration [FDA] approved); and
2. Any limitations on the information presented, such as data that are preliminary or that represent ongoing research, interim analyses, and/or unsupported opinion.

CME Inquiries

For all CME policy-related inquiries, please contact us at ce@affinityced.com.

Participation Costs

There is no cost to participate in this program.

To Earn CME Credit

1. Review the program materials
2. Click the green button on the right to "Claim CME credit"
3. Complete the Post-Test; this test features real-time learning. You will receive immediate feedback and rationales explaining the correct answers as you go. The requirement is 70% accuracy.
4. Once you have successfully passed the test and completed the required CME evaluation, your certificate will be available for download and emailed to you.

Disclaimer
This activity is intended for educational purposes only and does not establish a standard of care or replace clinical judgment. Any therapeutic or diagnostic strategies discussed must be evaluated in the context of each patient’s clinical circumstances, risks, and current evidence.

Learners should consult authoritative clinical guidelines and approved product information when considering treatment decisions.

All materials are used with permission. The views expressed are those of the faculty and do not necessarily reflect those of the accredited providers, MedAll, or any supporters.