Home
This site is intended for healthcare professionals
Sign up Log in

Growth Hormone Deficiency - Making A Diagnosis

  1. Welcome to a new accredited tweetorial on Growth Hormone Deficiency in anticipation of our GHD Academy going live on March 19th in collaboration with the wonderful Human Growth Foundation. This tweetorial provides 0.25 AMA PRA Category 1 Credits. #CME.

  2. Statement of accreditation and disclosures can be found at https://app.medall.org/c/medall-endocrinology/resources/cme-growth-disorders. This program has been supported by an independent medical education grant from Novo Nordisk and is delivered in joint providership with AffinityCE So . . . How much do you know about diagnosis of #GHD? 🤔

  3. #GHD can impact growth & metabolic health. Accurate diagnosis requires integrating clinical signs, lab results, and genetic testing. Let’s dive into how to spot GHD and manage it effectively 👇#EndoTwitter #PedsEndo

  4. Clinical clues for pediatric #GHD: ✔️ Height velocity <4 cm/year ✔️ Hypoglycemia, prolonged jaundice, micropenis (infants) ✔️ Delayed tooth eruption, high-pitched voice ✔️ Midline defects (e.g., septo-optic dysplasia)

  1. 🔬 Confirming #GHD: ✔️ IGF-I, IGFBP-3 levels: Typically low ✔️ GH stimulation tests (Arginine, Clonidine, Glucagon) ✔️ Brain MRI: Evaluate pituitary structure (tumors, hypoplasia) ✔️ Genetic testing: GH-1, GHRHR, PROP1, and other gene mutations #Endocrinology

  2. ⚠️ Pitfalls in diagnosis: differentiate #GHD from: ✔️ Familial short stature ✔️ Constitutional growth delay ✔️ Systemic diseases (Crohn’s, renal disease, hypothyroidism) 🔎Comprehensive assessment prevents misdiagnosis & delays

  1. 🤔Not sure how to recognise constitutional growth delay vs #GHD?
  1. 🤔How about familial short stature vs #GHD?
  1. 🤔And the other endocrine causes of short stature vs #GHD?
  1. 📌 Key takeaway: Early & accurate diagnosis maximizes patient outcomes in GHD. Let’s keep the conversation going! What are your biggest clinical challenges in diagnosing GHD?

Join us LIVE on March 19th for a GHD Academy Session to discuss further!

  1. Thank you for participating in this tweetorial! We hope you are as excited about the future of #GHD as we are! Claim your FREE credit NOW at https://forms.gle/Z7gbiQmQramhS6Sn7 and follow us for more CE/#CME!